Friday, February 24, 2012

Thus, future studies will be necessary ...

Drink EAA (6 g essential amino acids acids/35 g sucrose) increased arterial phenylalanine and insulin concentrations, phenylalanine


balance the leg, and muscle protein synthesis when ingested 1 or 3:00 after a workout.immune system summary So drink EAA


promoted muscle anabolism, and the exact time of reception depending on the time after exercise (1 or 3:00) was not a result >>. << This study was conducted to assess the influence of drink EAA terms of response of muscle protein synthesis after exercise >> << instead to evaluate the effectiveness of components of the drink. It is likely that the effectiveness


drink was associated with the joint action of carbohydrates and amino acids. In the absence of increasing concentrations of amino acids >> << acids increase insulin has only minor effects on muscle protein synthesis (


), not the action of insulin seen in muscle protein synthesis when amino acid concentrations may fall (


). Consumption of carbohydrate drink after a workout with high concentrations of insulin in plasma, but no


increase muscle fractional synthetic rate (


), probably because of concomitant reduction in the concentration of amino acids (


). Insulin is necessary for muscle protein synthesis to continue, but it seems that insulin is the primary regulator. Thus, the concept of insulin plays a permissive role in muscle protein synthesis was nominated (


). In this study, the combination of the availability of amino acids, resistance exercise, and elevated concentrations of insulin


stimulate protein synthesis B € ј400 predrink% higher value when the drink is consumed 1 or 3:00 after a workout. Although the response was a transitional


This is the highest level of protein synthesis, we have already reported under any circumstances, it may show


interactive effect on the availability of amino acids, insulin and resistance exercise. We showed an increase in muscle protein synthesis >> << rest compared with values ​​in the following circumstances: physiological hyperinsulinemia on B € ј50% (


), resistance to the implementation of the B € ј100% (


), amino acid availability of B € ј150% (


), and the availability of amino acids after training at 200% (


). The potential interactive effect of hyperinsulinemia and increased availability of amino acids can be judged by parallel


trends in insulin concentrations (Fig.) and phenylalanine arteriovenous difference (figure) over time, whereas arterial phenylalanine concentration remains elevated long after The reaction net muscle protein synthesis >> << subsided (Figure). In a previous study, the flood of amino acid replacement does not increase muscle protein synthesis, while muscle protein synthesis is stimulated


flooding with essential amino acids (


). In addition, the use of 40 g of amino acids with a small step for 3 hours after exercise increased net muscle protein balance


with a drink of essential amino acids that provide the same response as a drink mixed amino acids (


). It therefore seems that the essential amino acids are the main stimulants of muscle protein synthesis and nonessential amino acids >> << not a necessary component. The mechanism (s) for essential amino acids stimulate muscle protein synthesis


unknown, although regulation of initiation of translation through initiation factors may be involved (,


). Whatever the mechanism, the time course of induction of muscle protein synthesis takes place almost instantaneously, as >> << Time course of increase in net muscle protein synthesis closely parallel to the absorption of the drink. In any case, the presence of


replacement of amino acids, apparently, not the speed limit for muscle protein synthesis after exercise, as shown by increased



R alanine in this study, although alanine was not provided . Terms EAA drink consumption did not affect the behavior of muscle balance or net synthesis of muscle protein. This >> << no effect can be predicted based on our previous observations that muscle fractional synthetic rate increased at least


48 hours after the attack, heavy exercise resistance (


). Thus, the protein synthetic machinery, seems primed and ready to improve protein synthesis after exercise, when


amino acids are available. However, the inhibitory effect on translation initiation immediately after treadmill exercise


(


), as reported in rats. Thus, future studies will be necessary to determine the use of amino acids immediately


postexercise will have the same anabolic response. According to the absorption of nitrogen through both legs can be estimated by calculating the ratio of phenylalanine absorption in both leg


and the number of phenylalanine contained in the drink. The area under the curve for phenylalanine balance on


both feet was calculated for 3 hours after the EAA drink given postexercise 1:00. Total >> << phenylalanine was examined B ј21BЂ € "26% of phenylalanine in beverages. Assuming that this figure corresponds to >> << essential amino acids in the drink, and if we know that the drink contains EAA B € ј827 mg of nitrogen, we can calculate that


B € ј211 mg nitrogen raised feet for 3 hours after taking the drink. When we were given a drink containing bolus


13 g EAA and 35 g of sugar for the rest of healthy people, the ratio of absorption of nitrogen on nitrogen intake is 17% (


). Thus, the EAA drink in this study were more effective in oral administration after exercise compared with when hit >> << while resting (


). Whereas in the first pass splanchnic bed extracts 30% of ingested phenylalanine (


), it seems that amino acids that actually enter the bloodstream very high share being specifically taken up by


feet. In addition, the lack of growth or alanine or urea production after drink supports >> << conclude that the amino acids incorporated into proteins, in contrast to Katabolizuye. In contrast, urea production increased significantly when


40 g whey protein falls under the same protocol as used in this study (unpublished results). Thus, the use of 6 g lasix 50 mg essential amino acids with carbohydrates 1 or 3:00 after exercise increased blood


phenylalanine and insulin concentrations, phenylalanine balance the leg, and the synthesis of muscle protein. These results


indicate that the use of essential amino acids combined with carbohydrates 1 or 3:00 after exercise promotes muscle anabolism


by increasing muscle protein synthesis. .


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